Compositions and methods for improved glycoprotein sialylation
US8273723B2 · kind B2 · utility
5Cited by
5References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 13, 2008 |
| Grant date | Sep 25, 2012 |
| Priority date | — |
| Expiry date | Jan 8, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for the production of glycoproteins with enhanced sialylation. In particular, the invention provides cell lines comprising disrupted sialidase expression and methods of using the cell lines to produce glycoproteins with enhanced sialylation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.