Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics
US8273733B2 · kind B2 · utility
4Cited by
3References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 8, 2010 |
| Grant date | Sep 25, 2012 |
| Priority date | — |
| Expiry date | Oct 8, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure relates to tetrahydroisoquinoline sulfonamide compounds of formula I:wherein R1, R2, n and B are as defined in the disclosure, their preparation and their use in therapies for the treatment of central nervous system diseases such as vigilance and sleep disorders, narcolepsy, Alzheimer's disease and other dementias, Parkinson's disease, attention disorders in hyperkinetic children, memory and learning disorders, epilepsy, schizophrenia, moderate cognitive disorders, depression, anxiety, sexual dysfunction, dizziness and travel sickness.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.