Nano/macroporous bone tissue scaffolds for regenerative medicine
US8277829B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 30, 2007 |
| Grant date | Oct 2, 2012 |
| Priority date | — |
| Expiry date | Aug 11, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A biocompatible inorganic porous material having a three-dimensional coexistent network of interconnected macro-pores and nanopores produced by the steps of mixing an organic water-soluble polymer (e.g., polyethylene oxide or a block copolymer of ethylene oxide and propylene oxide), an alkoxysilane, and an inorganic water-soluble calcium salt in an aqueous acid solution, such that a sol-gel process of hydrolysis and polycondensation is initiated and thereby producing a gel; drying the gel to remove solvent by evaporation; and heating the gel to remove the polymer by thermal decomposition, thereby forming an inorganic porous material, which may be suitable for use as a bone tissue scaffold.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.