Methods of making frozen tissue microarrays
US8278034B2 · kind B2 · utility
43Cited by
17References
13Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 22, 2001 |
| Grant date | Oct 2, 2012 |
| Priority date | — |
| Expiry date | Jun 22, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6883
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides microarrays comprising a plurality of frozen tissues and/or cell samples and methods of preparing and using the same. By using frozen samples, the microarrays provide optimal samples from which to detect the expression of both nucleic acids (e.g., mRNAs) and proteins in high throughput parallel analyses. The microarrays enable gene identification, molecular profiling, selection of promising drug targets, sorting and prioritizing of expressed sequence array data, and the identification of abnormal physiological processes associated with disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.