Patent · US Active

Methods and device for analyte characterization

US8278055B2 · kind B2 · utility

17Cited by
19References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 29, 2003
Grant dateOct 2, 2012
Priority date—
Expiry dateSep 26, 2029

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/6818
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The methods and apparatus, disclosed herein are of use for sequencing and/or identifying proteins, polypeptides and/or peptides. Proteins containing labeled amino acid residues may be synthesized and passed through nanopores. A detector operably coupled to a nanopore may detect labeled amino acid residues as they pass through the nanopore. Distance maps for each type of labeled amino acid residue may be compiled. The distance maps may be used to sequence and/or identify the protein. Apparatus of use for protein sequencing and/or identification is also disclosed herein. In alternative methods, other types of analytes may be analyzed by the same techniques.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.