Method to enhance hemodynamic stability using oxygen carrying compositions
US8278275B2 · kind B2 · utility
1Cited by
20References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 23, 2009 |
| Grant date | Oct 2, 2012 |
| Priority date | — |
| Expiry date | Sep 20, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P41/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods for enhancing the hemodynamic stability of an individual undergoing surgery by administering a composition comprising a hemoglobin-based oxygen carrier. In one embodiment, the present invention relates to the use of polyalkylene oxide modified hemoglobins with reduced cooperativity and a high oxygen affinity to enhance oxygen offloading as a preventative measure to avoid hemodynamic stability-related complications during surgery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.