Patent · US Active

siRNA compounds for inhibiting NRF2

US8278287B2 · kind B2 · utility

3Cited by
23References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 6, 2009
Grant dateOct 2, 2012
Priority date
Expiry dateApr 24, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/344
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides chemically modified siRNA compounds that target the Nrf2 gene and pharmaceutical compositions comprising same useful for treating or preventing the incidence or severity of a cancerous disease, particularly various lung cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.