Patent · US Active

Spider silk proteins and methods for producing spider silk proteins

US8278416B1 · kind B1 · utility

5Cited by

3References

9Claims

0Family size

Assignee

SPIBER TECHNOLOGIES AB · SE

Inventors

Jan Johansson · Stockholm, SE
Göran Hjälm · Uppsala, SE
Margareta Stark · Stuvsta-Snättringe, SE
Anna Rising · Uppsala, SE
Stefan Grip · Uppsala, SE
Wilhelm Engström · Boo, SE
My Hedhammar · Stockholm, SE

Key dates

Filing date	Apr 6, 2012
Grant date	Oct 2, 2012
Priority date	—
Expiry date	Apr 6, 2032

Classification

Technology area (CPC D)Textiles; Paper
CPC primaryD01F4/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides an isolated major ampullate spidroin protein, which consists of from 150 to 420 amino acid residues and is defined by the formula REP-CT. REP is a repetitive, N-terminally derived protein fragment having from 80 to 300 amino acid residues. CT is a C-terminally derived protein fragment having from 70 to 120 amino acid residues. The invention further provides an isolated fusion protein consisting of a first protein fragment, which is a major ampullate spidroin protein, and a second protein fragment comprising a fusion partner and a cleavage agent recognition site. The first protein fragment is coupled via said cleavage agent recognition site to the fusion partner. The invention also provides a method of producing a major ampullate spidroin protein and polymers thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.