Patent · US Active

Pancreatin and method for reducing the viral and microbial contamination of pancreatin

US8283147B2 · kind B2 · utility

1Cited by

2References

50Claims

0Family size

Assignee

Nordmark Arzneimittel GmbH & Co. KG · DE

Inventors

Manfred Kurfürst · Moorrege, DE
Christian Rämsch · Uetersen, DE
Thomas Schräder · Uetersen, DE
Thomas Moest · Moorrege, DE

Key dates

Filing date	Mar 13, 2009
Grant date	Oct 9, 2012
Priority date	—
Expiry date	Sep 10, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2/0023
WIPO fieldMedical technology
WIPO sectorInstruments

Abstract

The invention relates to a method for producing pancreatin with reduced viral and microbial contamination, comprising the steps of (a) providing the pancreatin in solid form with a residual moisture of 0.5 weight % or less, down to almost zero, based on the pancreatin provided; (b) subjecting the pancreatin provided in step (a) to a heat treatment at a temperature of 84° C., preferably 80° C. and below; wherein, the biological activity of the pancreatin obtained in step (b) corresponds to at least 50% of the biological activity of the pancreatin provided in step (a); and the viral infectiousness of the pancreatin obtained in step (b) has been reduced by a factor of more than 1 log10 in comparison with the viral infectiousness of the pancreatin provided in step (a), as well as a pancreatin produced according to this method and its use for producing a medicine or a nutritional supplement.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.