Method for production of dendritic cell
US8283163B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 12, 2008 |
| Grant date | Oct 9, 2012 |
| Priority date | — |
| Expiry date | May 12, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods for producing DCs, which comprise the step of culturing DC precursor cells in the presence of multiple cytokines, dendritic cells produced thereby, and uses thereof. The methods of the present invention enable production of large quantities of DC precursors with a high ability to differentiate into DCs. The present invention enables one to obtain large quantities of DCs from a small number of DC precursor cells, and therefore makes it easier to increase the number of DCs for administration in DC-based anti-tumor immunotherapy, treatment of infection, and such. Thus, an enhancement is expected for the effect of DC vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.