Patent · US Active

N-sulfonamido polycyclic pyrazolyl compounds

US8283358B2 · kind B2 · utility

0Cited by

0References

24Claims

0Family size

Assignee

Elan Pharmaceuticals, Inc. · US

Inventors

Andrei W. Konradi · Burlingame, US
Xiaocong Michael Ye · Palo Alto, US
Simeon Bowers · Oakland, US
Albert W. Garofalo · South San Francisco, US
Danielle Aubele · Burlingame, US
Darren B. Dressen · San Francisco, US
Raymond Ng · San Ramon, US
Gary Probst · San Francisco, US
Christopher Semko · Fremont, US
Minghua Sun · Libertyville, US
Anh Truong · Burlingame, US
Michael S. Dappen · Daly City, US

Key dates

Filing date	Sep 4, 2009
Grant date	Oct 9, 2012
Priority date	—
Expiry date	Dec 16, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D451/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The current invention provides compounds having a structure according to Formulae 1, 2, 3, and 4:wherein the A-ring, B-ring, C-ring, m, n, R25, R50, and R51 are as described in the specification. The invention also provides pharmaceutical compositions comprising compounds of Formulae 1, 2, 3, and 4, as well as methods of treating cognitive disorders, such as Alzheimer's disease. The invention further provides intermediates useful in preparing the compounds of Formulae 1, 2, 3, and 4.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.