PD-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
US8287856B2 · kind B2 · utility
48Cited by
25References
18Claims
0Family size
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Key dates
| Filing date | Jul 19, 2010 |
| Grant date | Oct 16, 2012 |
| Priority date | — |
| Expiry date | Jul 19, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2239/57
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.