Sulfotransferase inhibitors

US8288139B2 · kind B2 · utility

Assignee

• SEIKAGAKU CORPORATION · JP

Inventors

• Osami Habuchi · Nagoya, JP
• Hirofumi Nakano · Machida, JP
• Toshihiko Sawada · Shitara, JP
• Sonoko Fujii · Marugame, JP
• Shiori Ohtake · Steubenplatz, JP

Key dates

• Filing date: Aug 19, 2008
• Grant date: Oct 16, 2012
• Expiry date: Jan 16, 2029

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A galactosamine derivative represented by the following formula (1):wherein R1, R2 and R5 each independently represents SO3− or H, and at least one of them represents SO3−; R3 represents H, acetyl or SO3−; R4 represents H, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted alkynyl group, a substituted or unsubstituted acyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aralkyl group; X represents O, S, NH or CH2; and represents an α bond or a β bond, and a sulfotransferase inhibitor comprising the derivative.