Pyrrolidines and piperidines as orexin receptor antagonists

US8288411B2 · kind B2 · utility

Assignee

• Actelion Pharmaceuticals Ltd. · CH

Inventors

• Hamed Aissaoui · Allschwil, CH
• Christoph Boss · Allschwil, CH
• Ralf Koberstein · Bad Kötzting, DE
• Thierry Sifferlen · Allschwil, CH

Key dates

• Filing date: Sep 23, 2008
• Grant date: Oct 16, 2012
• Expiry date: May 3, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of formula (I) wherein Y, A, N and R1 are as described in the description, to salts, especially pharmaceutically acceptable salts, of such compounds and to the use of such compounds as medicaments, especially as orexin receptor antagonists.