Process for the preparation a ruthenium complex

US8288534B2 · kind B2 · utility

Assignee

• Roche Palo Alto LLC · US

Inventors

• Angelino Doppiu · Seligenstadt, DE
• Ralf Karch · Kleinostheim, DE
• Kurt Puentener · Basel, CH
• Andreas Rivas-Nass · Schriesheim, DE
• Michelangelo Scalone · Birsfelden, CH
• Roland Winde · Frankfurt, DE
• Eileen Woerner · Nidderau, DE

Key dates

• Filing date: May 6, 2010
• Grant date: Oct 16, 2012
• Expiry date: Dec 4, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F15/0046
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a novel process for the preparation of Ruthenium metathesis catalysts of the formulaRuthenium metathesis catalysts have been widely applied in the synthesis of macrocyclic drug compounds.