Process for the synthesis of (2S,3AR,7AS)-octahydro-1H-indole carboxylic acid as an intermediate for trandolapril

US8288565B2 · kind B2 · utility

Assignee

• Abbott Laboratories · US

Inventors

• Sanjay R. Chemburkar · Gurnee, US
• Rajarathnam E. Reddy · Gurnee, US
• Douglas M. Reamer · North Chicago, US
• John T. Pavlina · Pleasant Prairie, US
• Stephen S. Ulrey · Lake Bluff, US
• Brian J. Kotecki · Oak Creek, US

Key dates

• Filing date: Jul 16, 2010
• Grant date: Oct 16, 2012
• Expiry date: Jul 16, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of (2S,3aR,7aS)-octahydro-1H-indole-20carboxylic acid hydrochloride.