Method and apparatus for thrombus removal using magnetic particles
US8293213B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 12, 2009 |
| Grant date | Oct 23, 2012 |
| Priority date | — |
| Expiry date | Nov 20, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2/06
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method and system for affecting a thrombus after ischemic stroke. The method may include injecting a plurality of magnetic particles into a bloodstream and moving or distorting a thrombus formed or lodged in the bloodstream using a magnetic force to manipulate the magnetic particles. The method may include conjugating ferromagnetic particles, paramagnetic particles, or superparamagnetic particles to a thrombus-specific attachment agent such as an anti-fibrin antibody, and injecting the conjugated particles into the bloodstream. Thereafter, the thrombus may be agitated, broken apart, or dissolved using a magnetic field to exert a magnetic force on the conjugated particles. The method may also include injecting a thrombolytic agent into the bloodstream to interact with and further dissolve the thrombus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.