Attenuated uracil auxotroph of an apicomplexan and use thereof
US8293224B2 · kind B2 · utility
3Cited by
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5Claims
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Key dates
| Filing date | Dec 21, 2007 |
| Grant date | Oct 23, 2012 |
| Priority date | — |
| Expiry date | Jun 10, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Uracil auxotroph mutants of apicomplexans are provided which lack a functional carbamoyl phosphate synthase II (CPSII) enzyme. Also provided are T. gondii autoxtroph mutants which express exogenous antigens, and methods of protecting an animal against a T. gondii and non-T. gondii disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.