Humanization of rabbit antibodies using a universal antibody framework
US8293235B2 · kind B2 · utility
15Cited by
33References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 25, 2009 |
| Grant date | Oct 23, 2012 |
| Priority date | — |
| Expiry date | Jun 25, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a universal antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.