Controlled-release nanoparticulate compositions

US8293277B2 · kind B2 · utility

Assignee

• Alkermes Pharma Ireland Limited · IE

Inventors

• Jon Swanson · North Wales, US
• Rajeev Jain · Framingham, US
• Robert Hontz · Newtown Square, US
• John Devane · Dublin, IE
• Kenneth Iain Cumming · Dublin, IE
• Maurice Joseph Anthony Clancy · Celbridge, IE
• Janet Elizabeth Codd · Athlone, IE
• Gary Liversidge · West Chester, US

Key dates

• Filing date: Jun 22, 1999
• Grant date: Oct 23, 2012
• Expiry date: Jun 22, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/2054
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent following administration for a time period ranging from about 2 to about 24 hours or longer.