Anti-bacterial composition especially for controlling gram-negative bacteria, comprising a peptide and an advantageously hydrophobic anti-bacterial agent
US8293700B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Aug 13, 2004 |
| Grant date | Oct 23, 2012 |
| Priority date | — |
| Expiry date | Nov 15, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to an anti-bacterial composition, especially for controlling gram-negative bacteria, containing a combination of: a) at least one peptide of between 10 and 25 amino acid residues comprising: i) two positively charged domains with a neutral pH consisting of between 3 and 9 amino acid residues, at least two thirds thereof being cationic amino acids, ii) a group of two to three non-cationic amino acid residues located between said positively charged domains, iii) a group of between 0 and 10, preferably between 0 and 5, amino acid residues selected from the group comprising non-hydrophobic amino acids and positively charged amino acids, located at one of the terminal ends N or C of the peptide, a positively charged amino acid residue, however, not being directly adjacent to the positively charged domains; and b) at least one anti-bacterial compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.