Compounds, pharmaceutical composition and methods relating thereto

US8293729B2 · kind B2 · utility

Assignees

• Boehringer Ingelheim International GmbH · DE
• Neurocrine Biosciences, Inc. · US

Inventors

• Brian Dyck · San Diego, US
• Joe Tran · Livermore, US
• Junko Tamiya · Carlsbad, US
• Florence Jovic · Los Angeles, US
• Troy Vickers · San Diego, US
• Chen Chen · San Diego, US
• Nicole Harriott · San Diego, US
• Timothy Richard Coon · Carlsbad, US
• Neil Ashweek · San Diego, US

Key dates

• Filing date: Jun 23, 2010
• Grant date: Oct 23, 2012
• Expiry date: Mar 11, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New compounds are disclosed which have utility in the treatment of a variety of metabolic related conditions in a patient. The compounds of this invention have the structure (I):wherein R1, R2, R3, n, p, q, and Ar are as defined herein, including stereoisomers, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising a compound of this invention, as well as methods relating to the use thereof in a patient in need thereof.