Patent · US Active

Isoquinolinopyrrolopyridinones active as kinase inhibitors

US8293762B2 · kind B2 · utility

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13Claims
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Assignee

Inventors

Key dates

Filing dateFeb 18, 2008
Grant dateOct 23, 2012
Priority date
Expiry dateJun 24, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Heteroarylpyridinone derivatives represented by formula (I)wherein R1, R2, R3, R4, R5, and X are as defined in the specification, compositions thereof, and methods of use thereof. Particularly, there are described isoquinolinoyrrolopyridinones, pharmaceutical compositions including them and their use as therapeutic agents in the treatment of cancer and cell proliferation disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.