Patent · US Active

4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide acid addition salts as kinase inhibitors

US8293767B2 · kind B2 · utility

2Cited by
23References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 22, 2011
Grant dateOct 23, 2012
Priority date
Expiry dateJul 22, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides an acid addition salt of 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide and crystals thereof, the salt being formed with an acid selected from methanesulphonic acid and acetic acid and mixtures thereof.Also provided are the novel uses of salts of 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide, processes for the preparation of 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide and its salts and novel chemical intermediates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.