Patent · US Active

Osmotic device containing a venlafaxine salt and a salt having an ion in common

US8293799B2 · kind B2 · utility

8Cited by
16References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 13, 2004
Grant dateOct 23, 2012
Priority date
Expiry dateFeb 14, 2029

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/277
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The osmotic devices of the present invention include a single core comprising a salt of a drug and an osmotic salt, wherein the drug salt and the osmotic salt have a common ion. The release rate of the active drug is reduced, and the release profile of the active drug is modified, from a first order release profile to a zero order, pseudo-zero order, or sigmoidal release profile, by increasing the amount of the sodium chloride in the core of the device. In one embodiment the sodium chloride is used to modify a controlled release profile to a delayed and controlled release profile.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.