Osmotic device containing a venlafaxine salt and a salt having an ion in common
US8293799B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 13, 2004 |
| Grant date | Oct 23, 2012 |
| Priority date | — |
| Expiry date | Feb 14, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/277
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The osmotic devices of the present invention include a single core comprising a salt of a drug and an osmotic salt, wherein the drug salt and the osmotic salt have a common ion. The release rate of the active drug is reduced, and the release profile of the active drug is modified, from a first order release profile to a zero order, pseudo-zero order, or sigmoidal release profile, by increasing the amount of the sodium chloride in the core of the device. In one embodiment the sodium chloride is used to modify a controlled release profile to a delayed and controlled release profile.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.