Process for producing cisatracurium compounds and associated intermediates

US8293912B2 · kind B2 · utility

Assignee

• Chemagis Ltd. · IL

Inventors

• Vladimir Naddaka · Netanya, IL
• Shen Jingshan · Shanghai, CN
• Oded Arad · Rehovot, IL
• Guo Hongli · Shanghai, CN
• Ofer Sharon · Netanya, IL
• Eyal Klopfer · Nes Ziona, IL
• Shady Saeed · Haifa, IL

Key dates

• Filing date: May 1, 2008
• Grant date: Oct 23, 2012
• Expiry date: Feb 21, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D217/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides processes for producing isoquinolinium compounds, and for converting them into cisatracurium salts, e.g., cisatracurium besylate