Patent · US Active

Compounds and compositions as channel activating protease inhibitors

US8293915B2 · kind B2 · utility

1Cited by

9References

12Claims

0Family size

Assignee

IRM Inc. · BM

Inventors

David C. Tully · San Diego, US
Arnab K. Chatterjee · Encinitas, US
Zhiwei Wang · Beijing, CN

Key dates

Filing date	Jan 7, 2008
Grant date	Oct 23, 2012
Priority date	—
Expiry date	Jun 29, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for, using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.