Adhesive pharmaceutical preparation containing bisoprolol
US8298572B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 13, 2006 |
| Grant date | Oct 30, 2012 |
| Priority date | — |
| Expiry date | Dec 4, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In the adhesive pharmaceutical preparation of the invention containing bisoprolol, a pressure-sensitive adhesive layer is laminated on one side of the backing. The pressure-sensitive adhesive layer contains a branched monoalcohol having from 12 to 28 carbon atoms, a free base of bisoprolol and a polyisobutylene pressure-sensitive adhesive. Accordingly, compatibility of the polyisobutylene pressure-sensitive adhesive with the free base of bisoprolol can be specifically increased. As a result, not only it becomes possible to increase blending amount of the free base of bisoprolol but also bleed of the free base of bisoprolol from the pressure-sensitive adhesive layer can be suppressed and, what is more, the pressure-sensitive adhesion characteristics sufficient from the practical point of view can be obtained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.