Compositions and methods for intramolecular nucleic acid rearrangement
US8298767B2 · kind B2 · utility
323Cited by
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18Claims
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Key dates
| Filing date | Aug 13, 2010 |
| Grant date | Oct 30, 2012 |
| Priority date | — |
| Expiry date | Aug 13, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/686
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Aspects of the present invention are drawn to processes for moving a region of interest in a polynucleotide from a first position to a second position with regard to a domain within the polynucleotide, also referred to as a “reflex method”. In certain embodiments, the reflex method results in moving a region of interest into functional proximity to specific domain elements present in the polynucleotide (e.g., primer sites and/or MID). Compositions, kits and systems that find use in carrying out the reflex processes described herein are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.