Methods of evaluating a test agent in a diseased cell model
US8298824B2 · kind B2 · utility
3Cited by
14References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 20, 2011 |
| Grant date | Oct 30, 2012 |
| Priority date | — |
| Expiry date | Sep 20, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2535/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the tissues of the immune system in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates and other materials in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system, coupled with disease models to provide a more complete representation of an immune response.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.