Patent · US Active

Macrocyclic inhibitors of hepatitis C virus replication

US8299021B2 · kind B2 · utility

45Cited by

30References

2Claims

0Family size

Assignee

INTERMUNE, INC. · US

Inventors

Lawrence M. Blatt · San Francisco, US
Scott D. Seiwert · Pacifica, US
Steven W. Andrews · Longmont, US
Pierre Martin · Rheinfelden, CH
Andreas Schumacher · Weil am Rhein, DE
Bradley Barnett · Northglenn, US
C. Todd Eary · Longmont, US
Robert J. Kaus · Longmont, US
Timothy Kercher · Longmont, US
Weidong Liu · Superior, US
Michael Lyon · Boulder, US
Paul Nichols · Firestone, US
Bin Wang · Beijing, CN
Tarek Sammakia · Boulder, US
April L. Kennedy · Denver, US
Yutong Jiang · Boulder, US

Key dates

Filing date	Apr 19, 2012
Grant date	Oct 30, 2012
Priority date	—
Expiry date	Apr 19, 2032

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The embodiments provide compounds of the general Formulae I through general Formula VIII, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.