Patent · US Active

Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers

US8299089B2 · kind B2 · utility

3Cited by

40References

23Claims

0Family size

Assignee

ENZON PHARMACEUTICALS, INC. · US

Inventors

Hong Zhao · Edison, US
Maria Belen Rubio · Somerville, US
Dechun Wu · Bound Brook, US
Puja Sapra · Edison, US

Key dates

Filing date	Apr 19, 2010
Grant date	Oct 30, 2012
Priority date	—
Expiry date	Jan 21, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/22
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A four arm-polyethylene glycol-7-ethyl-10-hydroxycamptothecin conjugate, such as,is disclosed. Methods of making the conjugates and methods of treating mammals using the same are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.