Water miscible solvent based process for purifying a bisphosphate
US8299149B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 21, 2009 |
| Grant date | Oct 30, 2012 |
| Priority date | — |
| Expiry date | Dec 21, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC09K21/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There is provided herein a process for purifying bisphosphate comprising solvating a molten bisphosphate in a mixture of water and water miscible solvent; cooling the solution over a period and to a temperature that provides for crystallization of solid product; increasing the pH of the solution prior to, and/or during, and/or after the initiation of crystallization, and/or after crystallization, by the addition of a base; and after crystallization is complete, separating solid product from the solution; washing the separated solid product in the same and/or different mixture of water and water miscible solvent; and, washing the solid product which has been washed in the mixture with water.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.