Stable micelles formed with diblock copolymers of critical micelle concentration copolymer and temperature-sensitive copolymer
US8299178B2 · kind B2 · utility
3Cited by
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11Claims
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Key dates
| Filing date | Mar 25, 2009 |
| Grant date | Oct 30, 2012 |
| Priority date | — |
| Expiry date | Jan 30, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel class of mixed micelles formed with critical micelle concentration (Cmc) character's diblock copolymer, and temperature-sensitive character's diblock copolymer were disclosed. The mixed micelles possess complementary effects in adjusting external temperature shift (storage vs. body temperature) and concentration change (dilution after intravenous injection). The mixed micelles of the present invention can serve as a potential injectable drug delivery system for anticancer drugs, such as doxorubicin and many others.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.