Wet granulation tableting method using aqueous dispersion of low-substituted hydroxypropyl cellulose
US8303868B2 · kind B2 · utility
12Cited by
5References
4Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 25, 2010 |
| Grant date | Nov 6, 2012 |
| Priority date | — |
| Expiry date | Jun 26, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2018
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a method for preparing a tablet having high tablet hardness and an excellent disintegration property even if low-substituted hydroxypropyl cellulose is added in a relatively small amount. More specifically, provided is a method for preparing a tablet comprising steps of granulating while spraying an aqueous dispersion of low-substituted hydroxypropyl cellulose having a degree of hydroxypropoxyl group substitution ranging from 5 to 16% by weight to a tablet-forming composition and tableting the resulting granules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.