Methods of inhibiting cell death or inflammation in a mammal by administering a BCL protein

US8304389B2 · kind B2 · utility

Assignee

• University of Washington through its Center for Commercialization, a Public Institution of Higher Education · US

Inventors

• John M. Harlan · Seattle, US
• Robert K. Winn · Bainbridge Island, US
• Akiko Iwata · Seattle, US
• Joan Tupper · Seattle, US
• John Li · Lawrence, US

Key dates

• Filing date: May 13, 2011
• Grant date: Nov 6, 2012
• Expiry date: May 13, 2031

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/5088
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

In one aspect the present invention provides methods for inhibiting cell death or inflammation in a mammal, wherein the methods each include the step of administering to a mammal a Bcl protein in an amount sufficient to inhibit cell death or inflammation in the mammal. The invention also provides methods for identifying a Bcl protein that inhibits cell death or inflammation when administered to a mammal.