Chromenone derivatives

US8304416B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Teresa Mujica-Fernaud · Darmstadt, DE
• Herwig Buchholz · Frankfurt am Main, DE
• Wilfried Rautenberg · Reinheim, DE
• Christian Sirrenberg · Darmstadt, DE

Key dates

• Filing date: Feb 15, 2011
• Grant date: Nov 6, 2012
• Expiry date: Feb 15, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel compounds of the formula Iin whichR1, R2, R3 and Het are as defined herein, whichare inhibitors of tyrosine kinases and/or Raf kinases and can be employed for the treatment of tumors, for neuroprotection and for protection of the stress proteins of the skin.