Pyrazolopyrimidinone kinase inhibitor
US8304418B2 · kind B2 · utility
0Cited by
17References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 28, 2008 |
| Grant date | Nov 6, 2012 |
| Priority date | — |
| Expiry date | Dec 18, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a novel pyrazolo[3,4-d]pyrimidin-4-one, specifically a derivative of 1-(pyridine-4-yl)-pyrazolo[3,4-d]pyrimidin-4-one. This compound is a kinase inhibitor that shows unexpected anti-proliferative activity against cells, including against tumor cells, and anti-tumor activity in xenograft tumor models. The compound or a suitable salt or prodrug thereof is useful for the treatment of individuals suffering from a cancer or another proliferative disorder or disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.