Method for making medical devices having antimicrobial coatings thereon

US8309117B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Michael F. Rubner · Westford, US
• Sung Yun Yang · Cambridge, US
• Yongxing Qiu · Duluth, US
• Lynn Cook Winterton · Roswell, US
• John Martin Lally · Lilburn, US

Key dates

• Filing date: Dec 10, 2003
• Grant date: Nov 13, 2012
• Expiry date: Apr 14, 2027

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/31692
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides a method for preparing a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating on a medical device, wherein the antimicrobial metal-containing LbL coating comprises at least one layer of a negatively charged polyionic material having —COOAg groups and/or silver nanoparticles formed by reducing Ag+ ions associated with the —COO− groups of the negatively charged polyionic material. In addition, the present invention provides a medical device prepared according to a method of the invention.