Patent · US Active

Methods of treating Parkinson's disease using viral vectors

US8309355B2 · kind B2 · utility

30Cited by

12References

12Claims

0Family size

Assignees

Genzyme Corporation · US
The Regents of the University of California · US

Inventors

Krys Bankiewicz · Garrett Park, US
Janet Cunningham · Alameda, US

Key dates

Filing date	Apr 10, 2009
Grant date	Nov 13, 2012
Priority date	—
Expiry date	Apr 10, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y401/01028
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods of delivering viral vectors, particularly recombinant AAV virions, to the central nervous system (CNS) are provided for the treatment of CNS disorders, particularly those disorders which involve the neurotransmitter dopamine. The methods entail providing rAAV virions that comprise a transgene encoding aromatic amino acid decarboxylase (AADC) and administering the virions to the brain of a mammal using a non-manual pump.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.