Patent · US Active

Quinuclidine compounds as α-7 nicotinic acetylcholine receptor ligands

US8309577B2 · kind B2 · utility

8Cited by

2References

18Claims

0Family size

Assignee

Bristol-Myers Squibb Company · US

Inventors

James H. Cook, II · East Hampton, US
Ivar M. McDonald · East Haddam, US
Dalton King · Hamden, US
Richard E. Olson · Wilmington, US
Nenghui Wang · Guilford, US
Christiana I. Iwuagwu · Wallingford, US
F. Christopher Zusi · Williamsville, US
John E. Macor · Guilford, US

Key dates

Filing date	Oct 28, 2009
Grant date	Nov 13, 2012
Priority date	—
Expiry date	Nov 7, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D519/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.