Methods for preparing 17-alkynyl-7-hydroxy steroids and related compounds
US8309746B2 · kind B2 · utility
2Cited by
17References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 5, 2009 |
| Grant date | Nov 13, 2012 |
| Priority date | — |
| Expiry date | Nov 2, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J75/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to processes for preparing 17-alkynyl-7-hydroxy-steroids, such as 17-Ethynyl-10R,13S-dimethyl 2,3,4,7,8R,9S, 10,11,12,13,14S,15,16,17-hexadecahydro-1H-cyclopenta[a]phenanthrene-3R, 7R,17S-triol (also referred to as 17α-ethynyl-androst-5-ene-3β,7β,17β-triol), that are essentially free of process impurities having binding activity at nuclear estrogen receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.