Method for the production of β-ketonitriles

US8309751B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Uwe Josef Vogelbacher · Ludwigshafen, DE
• Peter Otto · Gronau, DE
• Michael Rack · Eppelheim, DE

Key dates

• Filing date: Feb 29, 2008
• Grant date: Nov 13, 2012
• Expiry date: Nov 1, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for preparing β-ketonitriles of the general formula Iin which in which R1 has one of the meanings given above with a carboxylic ester of the formula IIIin which R2 has one of the meanings given above and R3 is C1-C12-alkyl, C1-C4-alkoxy -C1-C4-alkyl, C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C4-alkyl, phenyl-C1-C4-alkyl, phenoxy -C1-C4-alkyl or benzyloxy-C1-C4-alkyl,where the reaction is carried out in the presence of a potassium alkoxide and at least 80% of the nitrile of the formula II are added to the reaction under reaction conditions.