Fluorescent fiberoptic probe for tissue health discrimination and method of use thereof
US8311607B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Aug 22, 2011 |
| Grant date | Nov 13, 2012 |
| Priority date | — |
| Expiry date | Aug 22, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/7267
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at three selected wavelengths, one of which corresponds to an isosbestic point. In one example, the isosbestic point occurs at about 431 nm. The intensities of the observed signals are normalized using the 431 nm intensity. A score is determined using the ratios in a discriminant analysis. The tissue under examination is resected or not, based on the diagnosis of disease or health, according to the outcome of the discriminant analysis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.