Shiga toxin B-subunit as a vector for tumor diagnosis and drug delivery to GB3 expressing tumors
US8313731B2 · kind B2 · utility
2Cited by
13References
12Claims
0Family size
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Key dates
| Filing date | Jun 13, 2011 |
| Grant date | Nov 20, 2012 |
| Priority date | — |
| Expiry date | Jun 13, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to new compounds for cancer therapy or diagnosis and more specifically to the use of a non-toxic B subunit of Shiga toxin mutant as a vector for diagnostic products or drugs in over-expressing Gb3 receptor cells, such compounds having the following formula: STxB-Z(n)-Cys-Y(m)-T wherein
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.