Antikine antibodies that bind to multiple CC chemokines
US8313747B2 · kind B2 · utility
6Cited by
3References
50Claims
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Key dates
| Filing date | Aug 27, 2010 |
| Grant date | Nov 20, 2012 |
| Priority date | — |
| Expiry date | Nov 24, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/523
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An antikine antibody binds to two, three, four, five or more CC chemokines, such as RANTES/CCL5, MIP-1α/CCL3, MIP-1β/CCL4, or MCP-1/CCL2. Methods for affinity maturation and humanization of antikine antibodies as well as the production of hybridoma cell lines producing antikine antibodies by sequential immunization are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.