Sustained delivery formulations of rapamycin compounds
US8313763B2 · kind B2 · utility
31Cited by
94References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 15, 2007 |
| Grant date | Nov 20, 2012 |
| Priority date | — |
| Expiry date | Jun 26, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2210/0004
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a rapamycin sustained release delivery system for treatment of diseases responsive to rapamycin. The sustained release delivery system of the invention includes a flowable composition containing rapamycin or a rapamycin derivative, which is capable of providing an implant containing the rapamycin or derivative thereof. The flowable composition may be injected into tissue whereupon it coagulates to become the solid or gel, monolithic implant. The flowable composition includes a biodegradable, thermoplastic polymer, an organic liquid and rapamycin or a rapamycin derivative.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.