Droplet-based surface modification and washing
US8313895B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 10, 2009 |
| Grant date | Nov 20, 2012 |
| Priority date | — |
| Expiry date | Jan 10, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/00237
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to droplet-based surface modification and washing. According to one embodiment, a method of providing a bead-containing droplet with a reduced concentration of a substance is provided, the method including providing a droplet microactuator including a droplet having a starting volume and including one or more beads and a starting concentration and starting quantity of the substance. The method further includes conducting one or more droplet operations to merge a wash droplet with the droplet provided in the above step to yield a combined droplet and including one or more droplet operations to divide the combined droplet to yield a set of droplets including a droplet including substantially all of the one or more beads and having a decreased concentration of the substance relative to the starting concentration and a droplet which is substantially lacking in the beads.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.