Patent · US Active

Crystalline salts of quinoline compounds and methods for preparing them

US8314124B2 · kind B2 · utility

9Cited by

18References

23Claims

0Family size

Assignee

Active Biotech AB · SE

Inventors

Karl Jansson · Dalby, SE
Tomas Fristedt · Helsingborg, SE
Hans Wännman · Ängelholm, SE
Anders Bjork · Bjärred, SE

Key dates

Filing date	Mar 17, 2009
Grant date	Nov 20, 2012
Priority date	—
Expiry date	Feb 28, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D215/56
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A stable solid pharmaceutical composition consisting essentially of an effective amount of a crystalline salt of formula (II)together with an alkaline-reacting component maintaining the pH preferably above 8, or a salt with a divalent metal cation; andat least one pharmaceutical excipient;said salt of formula (II) being essentially stable during storage at room temperature for a period of at least 3 years. A process for stabilizing the salt of formula (II).A crystalline salt of formula (II) and a process for preparing said salt.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.