Preparation of 10-keto morphinans by benzylic oxidation
US8314237B2 · kind B2 · utility
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Key dates
| Filing date | Sep 7, 2010 |
| Grant date | Nov 20, 2012 |
| Priority date | — |
| Expiry date | Apr 1, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D489/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides processes for the preparation of 10-keto and/or 10-hydroxy morphinans. In particular, the invention provides to processes for preparing a 10-keto morphinan by chromium-catalyzed benzylic oxidation of a morphinan with a periodic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.